Mapping structure–function relationships within cerebellar circuits

Apps, R, Lawrenson, C.L, Paci, E ORCID: 0000-0002-6202-2825 and Cerminara, N.L (2022) 'Mapping structure–function relationships within cerebellar circuits.' In: Sillitoe, R.V, ed. Measuring cerebellar function. Humana, New York, NY, pp. 69-90. ISBN 9781071620250

Abstract

A key organizational feature of the cerebellum is its division into a series of cerebellar modules. The cortical component of each module is termed a zone. Each zone is defined by its climbing input originating from a well-defined region of the inferior olive, which targets one or more longitudinal zones of Purkinje cells within the cerebellar cortex. In turn, Purkinje cells within each zone project to specific regions of the cerebellar and vestibular nuclei. The behavioral significance of zones remains poorly understood. This chapter will describe approaches to physiologically and anatomically identify cerebellar cortical zones in both acute and chronic preparat ions (rat and cat) as well as methods to record from zones during behavior in order to determine the role that they have in cerebellar function.

Item Type:	Book Chapter or Section
Divisions:	School of Sciences
Date Deposited:	10 Mar 2025 18:23
Last Modified:	10 Mar 2025 18:23
URI / Page ID:	https://researchspace.bathspa.ac.uk/id/eprint/16936

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